After screening a library of over 100,000 small molecules, researchers from the Broad Institute of MIT and Harvard have identified compounds that act on a novel target in the malaria parasite, ...

Artemisinin-based combination treatments (ACTs) are seen as an important tool in the global effort to roll back malaria. With parasite resistance to chloroquine increasing rapidly in many parts of the ...

Malaria medicines that are too weak or downright fakes are harming health and could aggravate drug resistance, says epidemiologist Paul Newton It’s big. A recent review by the WorldWide Antimalarial ...

Among patients with incident rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) who were new antimalarial users, adherence to antimalarials (≥ 90% of doses) was associated with a lower ...

The most comprehensive international analysis on artemisinin combination antimalarials safety in pregnancy has now been released by researchers. Malaria is more common and severe in pregnant women, ...

New research published today in Antimicrobial Agents and Chemotherapy, shows that the well-established group of antimalarials, known as artemisinins, are unlikely to be affected by resistance. The ...

Malaria infection poses several risks for pregnant women and their unborn child. But they're often excluded in clinical trials due to safety concerns. A group of research experts have joined together ...

The battle to control malaria infection has been hampered by many factors, including emerging drug resistance. Now, two papers published in Nature have opened up the door to a wealth of compounds that ...

Malaria remains a serious global health threat. While the current discoveries of antimalarials are almost totally focused on single mode-of-action inhibitors, multi-targeting inhibitors are highly ...

Observational study results suggest antimalarials may have a broad protective effect against systemic damage in lupus nephritis. Among patients with biopsy-confirmed lupus nephritis, antimalarial ...