Relapsing after quitting cocaine is not simply a matter of willpower — it reflects physical changes in the brain, according ...

“I don’t understand why he just can’t stop abusing alcohol.” Turns out that addiction is a whole lot more complicated than just saying “no.” Although the stigma of addiction as a moral failing ...

A non-intoxicating compound in cannabis could offer a breakthrough treatment for alcohol use disorder. New research shows CBD ...

A mouse study highlights the role of acetylcholine in behavioral flexibility, offering new insight into the brain mechanisms involved in addiction and obsessive compulsive disorder.

The gut-brain-vagal axis The vagus nerve is the main pathway of the gut-brain axis, a complex communication network linking peripheral organs to the brain by transmitting interoceptive signals about ...

At 17, he started his long journey through addiction treatment units. Now 22, he has been treated numerous times in the ...

Most of the genetic risk for developing a substance use disorder comes from genes that broadly affect how our brains process rewards, regulate impulses and weigh consequences—not from genes that ...

Rutgers Brain Health Institute supports students through federally funded training grants, scholar programs, and ...

More than 48 million Americans are battling substance use disorder. Many are deteriorating in plain sight — on sidewalks, in ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target ...

In 1997, Alan Leshner, then director of the National Institute for Drug Abuse, wrote an article entitled “Addiction Is a Brain Disease and It Matters.” That eight-word title became the perfect sound ...