A study from Cornell researchers could enable a quantum leap forward in identifying and deciphering cancer-driving genetic ...

A previously unknown protein in a family of bacteria found in soil and the human gut microbiome has been discovered—which ...

In fact, each gene in cellular DNA contains the code for a unique protein structure. Not only are these proteins assembled with different amino acid sequences, but they also are held together by ...

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...

The researchers were able to purify these proteins and study their structure using cryo-electron ... of the molecule and then used high-performance computers to calculate a 3D structure with ...

“Not just the spatial structure of the protein but how it changes over time ... protein would have evolved with those particular amino acids in it to make those 3D patterns that allow it to fold,” ...

Why is knowing the atomic structure of molecules useful? Learn why, and how information like this about protein structure is shared through a publicly available database. Scientists use a variety ...

Learn about our Editorial Policies. On the same day that the AlphaFold2 paper was published, Baker and his colleagues released an independent, freely accessible alternative that predicts protein ...

The authors discovered that the genes at the formation of these loops are oriented towards each other. The formation mechanism of these loops is most likely related to a protein, RNA polymerase ...

Another protein, CTCF, attaches to locations of ... one genetic program to another—each defined by a particular 3D genome structure. "We are uncovering the language of cell memory and cell ...

In a paper published in PNAS, researchers at King's College London and the University of Washington describe the unique 3D structure of this protein, which is now being used to develop cancer drug ...